Overview

  • Product name
    Anti-RGS7BP antibody
  • Description
    Rabbit polyclonal to RGS7BP
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant fragment, corresponding to amino acids 86-178 of Human RGS7BP (Q6MZT1).

  • Positive control
    • Human hippocampus tissue; U 251 MG, Human liver and tonsil lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab150857 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/250. Predicted molecular weight: 29 kDa.
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Relevance
    Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes. When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cypolasmic shuttling. May also act by controlling the proteolytic stability of R7 proteins, probably by protecting them from degradation
  • Cellular localization
    Nucleus. Cytoplasm. Cell membrane; Lipid-anchor. Note: Shuttling between the plasma membrane, the cytoplasm and the nucleus is regulated by palmitoylation
  • Database links
  • Alternative names
    • R7 family-binding protein antibody
    • R7BP antibody
    • Regulator of G-protein signaling 7-binding protein antibody

Images

  • All lanes : Anti-RGS7BP antibody (ab150857) at 1/100 dilution

    Lane 1 : RT4 lysate
    Lane 2 : U 251 MG lysate
    Lane 3 : Human Plasma lysate
    Lane 4 : Human Liver lysate
    Lane 5 : Human Tonsil lysate


    Predicted band size : 29 kDa
  • Immunohistochemical analysis of Paraffin-embedded Human hippocampus tissue, labeling RGS7BP with ab150857 at 1/50 dilution.

References

ab150857 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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