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Mouse monoclonal [Rheb 3H6] to RHEB
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 1 µg/ml. Predicted molecular weight: 20 kDa.
||Use a concentration of 5 µg/ml.
Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Activates the protein kinase activity of mTORC1. Has low intrinsic GTPase activity.
Ubiquitous. Highest levels observed in skeletal and cardiac muscle.
Belongs to the small GTPase superfamily. Rheb family.
Farnesylation is important for efficiently activating mTORC1-mediated signaling.
Information by UniProt
- Ras homolog enriched in brain 2, formerly antibody
- GTP binding protein Rheb antibody
- GTP-binding protein Rheb antibody
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