Anti-Rho guanine exchange factor 16 antibody (ab104261)

Overview

  • Product name
    Anti-Rho guanine exchange factor 16 antibody
    See all Rho guanine exchange factor 16 primary antibodies
  • Description
    Rabbit polyclonal to Rho guanine exchange factor 16
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region between amino acids 175-225 of Human Rho guanine exchange factor 16 (NP_055263.2).

  • Positive control
    • Human Breast Carcinoma, Colon Carcinoma, Ovarian Carcinoma, Prostate Carcinoma, Small Cell Lung Cancer, Stomach Adenocarcinoma and Testicular Seminoma

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab104261 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer or tris-EDTA pH9.0 buffer will enhance staining.

Target

  • Function
    Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6.
  • Sequence similarities
    Contains 1 DH (DBL-homology) domain.
    Contains 1 PH domain.
    Contains 1 SH3 domain.
  • Domain
    The PDZ-binding motif mediates interaction with TAX1BP3.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARHGEF 16 antibody
    • ARHGEF16 antibody
    • ARHGG_HUMAN antibody
    • Ephexin 4 antibody
    • Ephexin-4 antibody
    • EPHEXIN4 antibody
    • GEF16 antibody
    • NBR antibody
    • Putative Neuroblastoma Protein antibody
    • Rho guanine exchange factor (GEF) 16 antibody
    • Rho guanine nucleotide exchange factor (GEF) 16 antibody
    • Rho guanine nucleotide exchange factor 16 antibody
    see all

Images

  • ab104261, at 1/250 dilution, staining Rho guanine exchange factor 16 in formalin-fixed, paraffin-embedded Human breast carcinoma by Immunohistochemistry using DAB staining.
  • ab104261, at 1/250 dilution, staining Rho guanine exchange factor 16 in formalin-fixed, paraffin-embedded Human colon carcinoma by Immunohistochemistry using DAB staining.

References

ab104261 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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