Biological descriptionNegative control for Rhodadyn™ C10 (ab120795). Demonstrates no significant inhibition of dynamin I or dynamin II in vitro GTPase activity at concentrations up to 300 μM and has no effect on clathrin-mediated endocytosis of transferrin when applied for 30 minutes to U2OS cells in culture.
Robertson J et al. The rhodadyn™ a new class of small molecule inhibitors of dynamin GTPase. ACS Med. Chem (2012).
General notesSold under exclusive licence from Children's Medical Research Institute and Newcastle Innovations Ltd. Rhodadyn™ is a trademark of Children's Medical Research Institute and Newcastle Innovation Ltd.
Storage instructionsStore at +4°C. Store under Desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.