Overview

  • Product name
  • Description
    Chicken polyclonal to Rhodopsin
  • Specificity
    ab28975 recognises opsin 1 (red cone photoreceptor).
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Zebrafish
  • Immunogen

    Synthetic peptide: YEDSTHASIFTYT, corresponding to amino acids 14/26 of Mouse Green cones Opsin 1; and synthetic peptide corresponding to amino acids 18/30 of tiger red cones opsin 1 were mixed and used as immunogen.

  • Positive control
    • mouse brain extract.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab28975 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: 1/500 - 1/2000. Predicted molecular weight: 40 kDa. To minimise background staining, it is recommended to use higher content of detergent Tween 20 to dilute the antibody and during washing.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal.
    • Tissue specificity
      Rod shaped photoreceptor cells which mediates vision in dim light.
    • Involvement in disease
      Retinitis pigmentosa 4
      Night blindness, congenital stationary, autosomal dominant 1
    • Sequence similarities
      Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
    • Post-translational
      modifications
      Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
      Contains one covalently linked retinal chromophore.
    • Cellular localization
      Membrane. Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to the rod outer segment (OS) photosensory cilia.
    • Information by UniProt
    • Database links
    • Alternative names
      • CSNBAD1 antibody
      • MGC138309 antibody
      • MGC138311 antibody
      • OPN 2 antibody
      • OPN2 antibody
      • opsd antibody
      • OPSD_HUMAN antibody
      • opsin 2 antibody
      • Opsin 2 rod pigment antibody
      • Opsin-2 antibody
      • Opsin2 antibody
      • Retinitis Pigmentosa 4 antibody
      • Retinitis pigmentosa 4 autosomal dominant antibody
      • RHO antibody
      • Rhodopsin antibody
      • RP 4 antibody
      • RP4 antibody
      see all

    References

    ab28975 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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