Overview

  • Product nameRhodopsin peptide

Description

  • NatureSynthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab4967 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Additional notes


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and bovine rhodopsin, catalog ab3424. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

General Info

  • Alternative names
    • CSNBAD1
    • MGC138309
    • MGC138311
    • OPN 2
    • OPN2
    • opsd
    • OPSD_HUMAN
    • opsin 2
    • Opsin 2 rod pigment
    • Opsin-2
    • Opsin2
    • Retinitis Pigmentosa 4
    • Retinitis pigmentosa 4 autosomal dominant
    • RHO
    • Rhodopsin
    • RP 4
    • RP4
    see all
  • FunctionPhotoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal.
  • Tissue specificityRod shaped photoreceptor cells which mediates vision in dim light.
  • Involvement in diseaseRetinitis pigmentosa 4
    Night blindness, congenital stationary, autosomal dominant 1
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family. Opsin subfamily.
  • Post-translational
    modifications
    Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
    Contains one covalently linked retinal chromophore.
  • Cellular localizationMembrane. Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to the rod outer segment (OS) photosensory cilia.
  • Information by UniProt

References for Rhodopsin peptide (ab4967)

ab4967 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting Abcam in regards to ab4967.
We have never tested this peptide in this particular application, so we cannot say whether it would work in this application or not.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"