Overview

  • Product name
    Anti-Rhophilin 2 antibody
  • Description
    Goat polyclonal to Rhophilin 2
  • Tested applications
    Suitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Cow
  • Immunogen

    Synthetic peptide:

    C-TNKNRQKSAST

    , corresponding to internal sequence amino acids 645-655 of Human Rhophilin 2 (NP_149094.2).

  • Positive control
    • Kidney tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab79011 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/32000.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function
    Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity.
  • Tissue specificity
    Widely expressed. Highly expressed in prostate, trachea, stomach, colon, thyroid and pancreas. Expressed at lower level in brain, spinal cord, kidney, placenta and liver.
  • Sequence similarities
    Belongs to the RHPN family.
    Contains 1 BRO1 domain.
    Contains 1 PDZ (DHR) domain.
    Contains 1 REM (Hr1) repeat.
  • Cellular localization
    Cytoplasm > perinuclear region.
  • Information by UniProt
  • Database links
  • Alternative names
    • 76 kDa RhoB effector protein antibody
    • D7Ertd784e antibody
    • GTP Rho binding protein 2 antibody
    • GTP-Rho-binding protein 2 antibody
    • p76RBE antibody
    • Rho GTPase binding protein 2 antibody
    • RhoB effector antibody
    • RhoBP antibody
    • Rhophilin 2 antibody
    • Rhophilin antibody
    • Rhophilin like protein antibody
    • Rhophilin like Rho GTPase binding protein antibody
    • Rhophilin Rho GTPase binding protein 2 antibody
    • Rhophilin-2 antibody
    • Rhophilin2 antibody
    • RHPN 2 antibody
    • RHPN2 antibody
    • RHPN2_HUMAN antibody
    see all

Images

  • ab79011, at 5µg/ml, staining Rhopilin 2 in kidney tissue by Immunohistochemistry using formalin-fixed, paraffin-embedded tissue.

References

ab79011 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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