Anti-Ribonuclease 7 antibody [3C2] (ab189222)

Overview

  • Product name
    Anti-Ribonuclease 7 antibody [3C2]
    See all Ribonuclease 7 primary antibodies
  • Description
    Mouse monoclonal [3C2] to Ribonuclease 7
  • Host species
    Mouse
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified) corresponding to Human Ribonuclease 7 aa 29-156. (Purified from cell culture supernatant).
    Database link: Q9H1E1

  • Positive control
    • Human Ribonuclease 7 expressed by CHOEBNALT85 cell line.

Properties

Applications

Our Abpromise guarantee covers the use of ab189222 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
WB 1/200 - 1/2000. Predicted molecular weight: 17 kDa.

1/500 to 1/2000 under non-reducing conditions; 1/200 to 1/1000 under reducing conditions.

Target

  • Function
    Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium.
  • Tissue specificity
    Expressed in various epithelial tissues including skin, respiratory tract, genito-urinary tract and, at a low level, in the gut. Expressed in liver, kidney, skeletal muscle and heart.
  • Sequence similarities
    Belongs to the pancreatic ribonuclease family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • EC 3.1.27.- antibody
    • MGC133220 antibody
    • Ribonuclease 7 antibody
    • ribonuclease, RNase A family, 7 antibody
    • RNAS7_HUMAN antibody
    • RNase 7 antibody
    • RNASE7 antibody
    • SAP 2 antibody
    • SAP-2 antibody
    • Skin derived antimicrobial protein 2 antibody
    • Skin-derived antimicrobial protein 2 antibody
    see all

Images

  • Lane 1 : Anti-Ribonuclease 7 antibody [3C2] (ab189222) at 1/500 dilution
    Lane 2 : Anti-Ribonuclease 7 antibody [3C2] (ab189222) at 1/200 dilution

    All lanes : Human RNase 7 expressed by CHOEBNALT85 cell line (cell culture supernatant)

    Lysates/proteins at 10 µl per lane.

    Predicted band size: 17 kDa



    Lane 1: Non-reduced conditions; Lane 2: Reduced conditions

References

ab189222 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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