Anti-Ribonuclease 7 antibody (ab81470)

Overview

  • Product name
    Anti-Ribonuclease 7 antibody
    See all Ribonuclease 7 primary antibodies
  • Description
    Rabbit polyclonal to Ribonuclease 7
  • Specificity
    ab81470 reacts with a 17 kDa Ribonuclease 7 protein. It also cross reacts with Ribonuclease 8 protein.
  • Tested applications
    Suitable for: IHC-Fr, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from the N terminal domain of human Ribonuclease 7

Properties

Applications

Our Abpromise guarantee covers the use of ab81470 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/200 - 1/1000.
WB 1/500 - 1/5000. Predicted molecular weight: 17 kDa.

Target

  • Function
    Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium.
  • Tissue specificity
    Expressed in various epithelial tissues including skin, respiratory tract, genito-urinary tract and, at a low level, in the gut. Expressed in liver, kidney, skeletal muscle and heart.
  • Sequence similarities
    Belongs to the pancreatic ribonuclease family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • EC 3.1.27.- antibody
    • MGC133220 antibody
    • Ribonuclease 7 antibody
    • ribonuclease, RNase A family, 7 antibody
    • RNAS7_HUMAN antibody
    • RNase 7 antibody
    • RNASE7 antibody
    • SAP 2 antibody
    • SAP-2 antibody
    • Skin derived antimicrobial protein 2 antibody
    • Skin-derived antimicrobial protein 2 antibody
    see all

Images

  • All lanes : Anti-Ribonuclease 7 antibody (ab81470) at 1/500 dilution

    Lane 1 : Human small intestine tissue lysate - total protein (ab29276)
    Lane 2 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Predicted band size : 17 kDa
    Observed band size : 17 kDa
    Additional bands at : 37 kDa,40 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 20 minutes

References

ab81470 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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