The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-RIC8 antibody (ab24383)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Protein Ric 8A
Protein Ric 8B
Resistance to inhibitors of cholinesterase 8 homolog A
Resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
Resistance to inhibitors of cholinesterase 8 homolog B
Resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
RelevanceRIC8 is a Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
The Caenorhabditis elegans protein Ric-8 has two mammalian homologs that have been identified : Ric-8A (Ric-8/synembryn) and Ric-8B. Synembryns are proteins that positively regulate synaptic transmission.
References for RIC8 peptide (ab45642)
has not yet been referenced specifically in any publications.
Publishing research using ab45642? Please let us know so that we can cite the reference in this datasheet.
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