• Product nameAnti-RIC8A antibody
    See all RIC8A primary antibodies
  • Description
    Rabbit polyclonal to RIC8A
  • Tested applicationsSuitable for: ICC/IF, IP, IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within amino acids 528 and 537 of Human RIC8A (NP_068751).

  • Positive control
    • A431, H1299, HeLa, HepG2 and Raji cell lines; Adrenal cortical tumor


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab97808 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration. PubMed: 24466196
IP Use at an assay dependent concentration. PubMed: 24466196
IHC-P 1/100 - 1/500.
WB 1/500 - 1/3000. Predicted molecular weight: 60 kDa.


  • FunctionGuanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
  • Sequence similaritiesBelongs to the synembryn family.
  • Cellular localizationCytoplasm. Cell membrane. Colocalizes with RIC8A in CA2 hippocampal neurons. Colocalizes with GNAI1 and RGS14 at the plasma membrane (By similarity).
  • Information by UniProt
  • Database links
  • Alternative names
    • MGC104517 antibody
    • MGC131931 antibody
    • MGC148073 antibody
    • MGC148074 antibody
    • Protein Ric-8A antibody
    • resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) antibody
    • RIC8 antibody
    • RIC8A antibody
    • RIC8A_HUMAN antibody
    • Synembryn-A antibody
    see all

Anti-RIC8A antibody images

  • All lanes : Anti-RIC8A antibody (ab97808) at 1/1000 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : HeLa whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size : 60 kDa
  • ab97808, at a 1/100 dilution, staining RIC8A in paraffin embedded Adrenal cortical tumor by Immunohistochemistry.

References for Anti-RIC8A antibody (ab97808)

This product has been referenced in:
  • Boularan C  et al. Resistance to inhibitors of cholinesterase (Ric)-8A and Gai contribute to cytokinesis abscission by controlling vacuolar protein-sorting (Vps)34 activity. PLoS One 9:e86680 (2014). WB, IP, ICC/IF ; Human . Read more (PubMed: 24466196) »

See 1 Publication for this product

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