Overview

  • Product nameAnti-RIN1 antibody
    See all RIN1 primary antibodies
  • Description
    Rabbit polyclonal to RIN1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-783 of Human RIN1 (NP_004283.2).

  • Positive control
    • IMR-32 cell lysate and RIN1 transfected 293T cell line lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab103151 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 84 kDa.

Target

  • RelevanceRIN1 is a Ras effector protein which can affect Ras signaling in a variety of ways. It enhances signaling from ABL1 and ABL2 whcih are involved in regulation of cytoskeletal remodeling. It may function as a guanine nucleotide exchange factor in activation of Rab5a. Rin1 also competes with RAF1 for binding of the activated form of Ras. It may play a role inhibiting the modulation of neuronal plasticity in formation of aversive memory, and has been implicated as a tumor supressor gene in breast cancer.
  • Cellular localizationCytoplasmic and Plasma membrane
  • Database links
  • Alternative names
    • Ras and Rab interactor 1 antibody
    • ras inhibitor 1 antibody
    • ras inhibitor antibody
    • Ras inhibitor JC99 antibody
    • ras inhibitor RIN1 antibody
    • Ras interaction/interference protein 1 antibody
    • RIN 1 antibody
    see all

Anti-RIN1 antibody images

  • Anti-RIN1 antibody (ab103151) at 1/500 dilution + IMR-32 cell lysate at 50 µg

    Predicted band size : 84 kDa
  • All lanes : Anti-RIN1 antibody (ab103151) at 1/500 dilution

    Lane 1 : RIN1 transfected 293T cell line
    Lane 2 : Non-transfected 293T cell line

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 84 kDa

References for Anti-RIN1 antibody (ab103151)

ab103151 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"