Overview

  • Product nameAnti-RIP2 antibody
    See all RIP2 primary antibodies
  • Description
    Mouse monoclonal to RIP2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 431-541 of Human RIP2

Properties

Applications

Our Abpromise guarantee covers the use of ab57952 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionActivates pro-caspase-1 and pro-caspase-8. Potentiates CASP8-mediated apoptosis. Activates NF-kappa-B.
    • Tissue specificityDetected in heart, brain, placenta, lung, peripheral blood leukocytes, spleen, kidney, testis, prostate, pancreas and lymph node.
    • Sequence similaritiesBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
      Contains 1 CARD domain.
      Contains 1 protein kinase domain.
    • Post-translational
      modifications
      Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.
      Ubiquitinated; undergoes 'Lys-63'-linked polyubiquitination catalyzed by ITCH.
    • Cellular localizationCytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • CARD 3 antibody
      • CARD carrying kinase antibody
      • CARD containing ICE associated kinase antibody
      • CARD containing IL 1 beta ICE kinase antibody
      • CARD containing IL1 beta ICE kinase antibody
      • CARD containing interleukin 1 beta converting enzyme (ICE) associated kinase antibody
      • CARD containing interleukin 1 beta converting enzyme associated kinase antibody
      • CARD-containing IL-1 beta ICE-kinase antibody
      • CARD-containing interleukin-1 beta-converting enzyme-associated kinase antibody
      • CARD3 antibody
      • CARDIAK antibody
      • CCK antibody
      • CLARP kinase antibody
      • GIG 30 antibody
      • GIG30 antibody
      • Growth inhibiting gene 30 antibody
      • Receptor interacting protein (RIP) like interacting caspase like apoptosis regulatory protein (CLARP) kinase antibody
      • Receptor interacting protein 2 antibody
      • Receptor interacting serine threonine kinase 2 antibody
      • Receptor interacting serine/threonine protein kinase 2 antibody
      • Receptor-interacting protein 2 antibody
      • Receptor-interacting serine/threonine-protein kinase 2 antibody
      • RICK antibody
      • RIP 2 antibody
      • RIP like interacting CLARP kinase antibody
      • RIP-2 antibody
      • RIP-like-interacting CLARP kinase antibody
      • RIPK 2 antibody
      • Ripk2 antibody
      • RIPK2_HUMAN antibody
      • TNFRSF antibody
      see all

    Anti-RIP2 antibody images



    • Predicted band size : 61 kDa
      RIP2 antibody (ab57952) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    References for Anti-RIP2 antibody (ab57952)

    ab57952 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"