Overview

  • Product name
    Anti-RITA antibody - N-terminal
    See all RITA primary antibodies
  • Description
    Rabbit polyclonal to RITA - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human RITA aa 43-72 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q96K30

  • Positive control
    • HL-60 cell line lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab170643 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 29 kDa.

Target

  • Function
    Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.
  • Sequence similarities
    Belongs to the RITA family.
  • Cellular localization
    Cytoplasm. Nucleus. Cytoplasm > cytoskeleton > centrosome. Shuttles rapidly between the cytoplasm and the nucleus. The function of centrosome localization is still unclear.
  • Information by UniProt
  • Database links
  • Alternative names
    • C12orf52 antibody
    • Chromosome 12 open reading frame 52 antibody
    • RBPJ interacting and tubulin associated 1 antibody
    • RBPJ interacting and tubulin associated protein 1 antibody
    • RBPJ-interacting and tubulin-associated protein antibody
    • RITA antibody
    • RITA_HUMAN antibody
    see all

Images

  • Anti-RITA antibody - N-terminal (ab170643) at 1/100 dilution + HL-60 cell line lysates at 35 µg

    Predicted band size: 29 kDa

References

ab170643 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab170643.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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