Anti-RNA polymerase II CTD repeat YSPTSPS (phospho S5) antibody - ChIP Grade (ab5131)

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ab5131 has been referenced in 90 publications.

  • Magbanua JP  et al. A variably occupied CTCF binding site in the ultrabithorax gene in the Drosophila bithorax complex. Mol Cell Biol 35:318-30 (2015). PubMed: 25368383
  • Bazot Q  et al. Epstein-Barr Virus Proteins EBNA3A and EBNA3C Together Induce Expression of the Oncogenic MicroRNA Cluster miR-221/miR-222 and Ablate Expression of Its Target p57KIP2. PLoS Pathog 11:e1005031 (2015). PubMed: 26153983
  • DeNicola GM  et al. NRF2 regulates serine biosynthesis in non-small cell lung cancer. Nat Genet N/A:N/A (2015). ChIP ; Mouse . PubMed: 26482881
  • Lee YL  et al. MAF1 represses CDKN1A through a Pol III-dependent mechanism. Elife 4:e06283 (2015). ChIP ; Human . PubMed: 26067234
  • Wei H  et al. Unique subcellular distribution of RPB1 with a phosphorylated C-terminal domain (CTD) in mouse oocytes during meiotic division and its relationship with chromosome separation. J Reprod Dev 61:541-8 (2015). WB, IHC-P ; Mouse . PubMed: 26346254
  • Castel SE  et al. Dicer promotes transcription termination at sites of replication stress to maintain genome stability. Cell 159:572-83 (2014). ChIP ; Schizosaccharomyces pombe . PubMed: 25417108
  • Parua PK  et al. Yeast 14-3-3 protein functions as a comodulator of transcription by inhibiting coactivator functions. J Biol Chem 289:35542-60 (2014). PubMed: 25355315
  • Khalouei S  et al. Localization of heat shock protein HSPA6 (HSP70B') to sites of transcription in cultured differentiated human neuronal cells following thermal stress. J Neurochem 131:743-54 (2014). PubMed: 25319762
  • Bonnay F  et al. Akirin specifies NF-?B selectivity of Drosophila innate immune response via chromatin remodeling. EMBO J 33:2349-62 (2014). ChIP ; Drosophila melanogaster . PubMed: 25180232
  • Brenachot X  et al. The histone acetyltransferase MOF activates hypothalamic polysialylation to prevent diet-induced obesity in mice. Mol Metab 3:619-29 (2014). ChIP ; Mouse . PubMed: 25161885
  • Margolin G  et al. Integrated transcriptome analysis of mouse spermatogenesis. BMC Genomics 15:39 (2014). ChIP ; Mouse . PubMed: 24438502
  • Predeus AV  et al. Targeted chromatin profiling reveals novel enhancers in Ig H and Ig L chain Loci. J Immunol 192:1064-70 (2014). Mouse . PubMed: 24353267
  • Dürr J  et al. The transcript elongation factor SPT4/SPT5 is involved in auxin-related gene expression in Arabidopsis. Nucleic Acids Res 42:4332-47 (2014). Arabidopsis thaliana . PubMed: 24497194
  • Murgatroyd C & Spengler D Polycomb binding precedes early-life stress responsive DNA methylation at the Avp enhancer. PLoS One 9:e90277 (2014). ChIP ; Mouse . PubMed: 24599304
  • Kapoor-Vazirani P & Vertino PM A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausing. J Biol Chem 289:7425-37 (2014). ChIP ; Human . PubMed: 24459145
  • Maganti N  et al. Nonproteolytic roles of 19S ATPases in transcription of CIITApIV genes. PLoS One 9:e91200 (2014). Human . PubMed: 24625964
  • Wang Y  et al. Super-resolution microscopy reveals decondensed chromatin structure at transcription sites. Sci Rep 4:4477 (2014). IF ; Human . PubMed: 24667378
  • Park D  et al. Simultaneous mapping of transcript ends at single-nucleotide resolution and identification of widespread promoter-associated non-coding RNA governed by TATA elements. Nucleic Acids Res 42:3736-49 (2014). ChIP ; Saccharomyces cerevisiae . PubMed: 24413663
  • Wolters S  et al. Loss of Caenorhabditis elegans BRCA1 promotes genome stability during replication in smc-5 mutants. Genetics 196:985-99 (2014). WB ; Caenorhabditis elegans . PubMed: 24424777
  • Long L  et al. The U4/U6 recycling factor SART3 has histone chaperone activity and associates with USP15 to regulate H2B deubiquitination. J Biol Chem 289:8916-30 (2014). PubMed: 24526689
  • Weiste C & Dröge-Laser W The Arabidopsis transcription factor bZIP11 activates auxin-mediated transcription by recruiting the histone acetylation machinery. Nat Commun 5:3883 (2014). ChIP . PubMed: 24861440
  • Hsieh CL  et al. Enhancer RNAs participate in androgen receptor-driven looping that selectively enhances gene activation. Proc Natl Acad Sci U S A 111:7319-24 (2014). PubMed: 24778216
  • Wang X  et al. A source of the single-stranded DNA substrate for activation-induced deaminase during somatic hypermutation. Nat Commun 5:4137 (2014). PubMed: 24923561
  • Yin T  et al. A novel CDK9 inhibitor shows potent antitumor efficacy in preclinical hematologic tumor models. Mol Cancer Ther 13:1442-56 (2014). PubMed: 24688048
  • Dottermusch-Heidel C  et al. H3K79 methylation directly precedes the histone-to-protamine transition in mammalian spermatids and is sensitive to bacterial infections. Andrology 2:655-65 (2014). ICC/IF ; Human . PubMed: 25079683
  • Kaminski TP  et al. Transcription regulation during stable elongation by a reversible halt of RNA polymerase II. Mol Biol Cell 25:2190-8 (2014). PubMed: 24850889
  • Lee SM  et al. HBx induces hypomethylation of distal intragenic CpG islands required for active expression of developmental regulators. Proc Natl Acad Sci U S A 111:9555-60 (2014). Mouse . PubMed: 24941955
  • Chou C  et al. c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8(+) T cells. Nat Immunol 15:884-93 (2014). PubMed: 25029552
  • Gyenis A  et al. UVB induces a genome-wide acting negative regulatory mechanism that operates at the level of transcription initiation in human cells. PLoS Genet 10:e1004483 (2014). WB ; Human . PubMed: 25058334
  • Amatori S  et al. PAT-ChIP coupled with laser microdissection allows the study of chromatin in selected cell populations from paraffin-embedded patient samples. Epigenetics Chromatin 7:18 (2014). ChIP ; Mouse . PubMed: 25104973
  • Xue Z  et al. Transcriptional interference by antisense RNA is required for circadian clock function. Nature N/A:N/A (2014). PubMed: 25132551
  • Taylor BJ  et al. Active RNAP pre-initiation sites are highly mutated by cytidine deaminases in yeast, with AID targeting small RNA genes. Elife 3:N/A (2014). ChIP ; Saccharomyces cerevisiae . PubMed: 25237741
  • Zaborowska J  et al. Herpes Simplex Virus 1 (HSV-1) ICP22 protein directly interacts with cyclin-dependent kinase (CDK)9 to inhibit RNA polymerase II transcription elongation. PLoS One 9:e107654 (2014). WB ; Human . PubMed: 25233083
  • Kreher S  et al. Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma. Proc Natl Acad Sci U S A 111:E4513-22 (2014). PubMed: 25288773
  • Henriquez B  et al. Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in developing hippocampal neurons. Mol Cell Neurosci 57:130-43 (2013). ChIP ; Rat . PubMed: 23932971
  • Schulze-Gahmen U  et al. The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat. Elife 2:e00327 (2013). WB ; Human . PubMed: 23471103
  • Eun B  et al. Promoter cross-talk via a shared enhancer explains paternally biased expression of Nctc1 at the Igf2/H19/Nctc1 imprinted locus. Nucleic Acids Res 41:817-26 (2013). IP ; Human . PubMed: 23221643
  • Khan P  et al. Mitogen- and stress-activated protein kinases 1 and 2 are required for maximal trefoil factor 1 induction. PLoS One 8:e63189 (2013). ChIP ; Human . PubMed: 23675462
  • Umlauf D  et al. The human TREX-2 complex is stably associated with the nuclear pore basket. J Cell Sci 126:2656-67 (2013). Human . PubMed: 23591820
  • Eun B  et al. The Igf2/H19 muscle enhancer is an active transcriptional complex. Nucleic Acids Res 41:8126-34 (2013). PubMed: 23842673
  • Verway M  et al. Vitamin D induces interleukin-1ß expression: paracrine macrophage epithelial signaling controls M. tuberculosis infection. PLoS Pathog 9:e1003407 (2013). ChIP ; Mouse . PubMed: 23762029
  • Largeot A  et al. Symplekin, a polyadenylation factor, prevents MOZ and MLL activity on HOXA9 in hematopoietic cells. Biochim Biophys Acta 1833:3054-3063 (2013). PubMed: 23994619
  • Subramanian V  et al. H2A.Z acidic patch couples chromatin dynamics to regulation of gene expression programs during ESC differentiation. PLoS Genet 9:e1003725 (2013). ChIP . PubMed: 23990805
  • Kearney SJ  et al. Type I IFNs downregulate myeloid cell IFN-? receptor by inducing recruitment of an early growth response 3/NGFI-A binding protein 1 complex that silences ifngr1 transcription. J Immunol 191:3384-92 (2013). PubMed: 23935197
  • Gupte R  et al. Glucocorticoid receptor represses proinflammatory genes at distinct steps of the transcription cycle. Proc Natl Acad Sci U S A 110:14616-21 (2013). PubMed: 23950223
  • Attema JL  et al. Identification of an Enhancer That Increases miR-200b~200a~429 Gene Expression in Breast Cancer Cells. PLoS One 8:e75517 (2013). PubMed: 24086551
  • Millán-Zambrano G  et al. The prefoldin complex regulates chromatin dynamics during transcription elongation. PLoS Genet 9:e1003776 (2013). ChIP ; Saccharomyces cerevisiae . PubMed: 24068951
  • Steenpass L  et al. Human PPP1R26P1 functions as cis-repressive element in mouse Rb1. PLoS One 8:e74159 (2013). ChIP . PubMed: 24019952
  • Burke SJ  et al. Regulation of iNOS gene transcription by IL-1ß and IFN-? requires a coactivator exchange mechanism. Mol Endocrinol 27:1724-42 (2013). IP . PubMed: 24014650
  • Caganova M  et al. Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis. J Clin Invest 123:5009-22 (2013). ChIP ; Mouse . PubMed: 24200695
  • Meyer KB  et al. Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1. Am J Hum Genet 93:1046-60 (2013). PubMed: 24290378
  • Park D  et al. Widespread misinterpretable ChIP-seq bias in yeast. PLoS One 8:e83506 (2013). ChIP ; Saccharomyces cerevisiae . PubMed: 24349523
  • Berlivet S  et al. Clustering of tissue-specific sub-TADs accompanies the regulation of HoxA genes in developing limbs. PLoS Genet 9:e1004018 (2013). ChIP ; Mouse . PubMed: 24385922
  • Vorobyeva NE  et al. SAYP and Brahma are important for 'repressive' and 'transient' Pol II pausing. Nucleic Acids Res 40:7319-31 (2012). PubMed: 22638575
  • Ehrensberger KM  et al. Zinc-dependent regulation of the adh1 antisense transcript in fission yeast. J Biol Chem : (2012). ChIP ; Schizosaccharomyces pombe . PubMed: 23223230
  • Miyanari Y & Torres-Padilla ME Control of ground-state pluripotency by allelic regulation of Nanog. Nature 483:470-3 (2012). PubMed: 22327294
  • Fleetwood MR  et al. DNase I Hypersensitive Site II of the Human Growth Hormone Locus Control Region Mediates an Essential and Distinct Long-range Enhancer Function. J Biol Chem 287:25454-65 (2012). ChIP . PubMed: 22669946
  • Rada-Iglesias A  et al. A unique chromatin signature uncovers early developmental enhancers in humans. Nature 470:279-83 (2011). ChIP ; Human . PubMed: 21160473
  • Sansó M  et al. Gcn5 facilitates Pol II progression, rather than recruitment to nucleosome-depleted stress promoters, in Schizosaccharomyces pombe. Nucleic Acids Res : (2011). PubMed: 21515633
  • Kapoor-Vazirani P  et al. SUV420H2-mediated H4K20 trimethylation enforces RNA polymerase II promoter-proximal pausing by blocking hMOF-dependent H4K16 acetylation. Mol Cell Biol 31:1594-609 (2011). PubMed: 21321083
  • Lin JJ  et al. Mediator coordinates PIC assembly with recruitment of CHD1. Genes Dev 25:2198-209 (2011). ChIP ; Human . PubMed: 21979373
  • Ram O  et al. Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells. Cell 147:1628-39 (2011). CHIPseq ; Human . PubMed: 22196736
  • Drobic B  et al. Promoter chromatin remodeling of immediate-early genes is mediated through H3 phosphorylation at either serine 28 or 10 by the MSK1 multi-protein complex. Nucleic Acids Res : (2010). ChIP ; Mouse . PubMed: 20129940
  • Sun J & Li R Human negative elongation factor activates transcription and regulates alternative transcription initiation. J Biol Chem 285:6443-52 (2010). ChIP ; Human . PubMed: 20028984
  • Mirabella F  et al. The human IL-3/granulocyte-macrophage colony-stimulating factor locus is epigenetically silent in immature thymocytes and is progressively activated during T cell development. J Immunol 184:3043-54 (2010). ChIP . PubMed: 20147630
  • Sohn BH  et al. Functional switching of TGF-beta1 signaling in liver cancer via epigenetic modulation of a single CpG site in TTP promoter. Gastroenterology 138:1898-908 (2010). ChIP ; Human . PubMed: 20038433
  • Rahl PB  et al. c-Myc regulates transcriptional pause release. Cell 141:432-45 (2010). WB, ChIP ; Mouse . PubMed: 20434984
  • Ali S  et al. The development of a selective cyclin-dependent kinase inhibitor that shows antitumor activity. Cancer Res 69:6208-15 (2009). WB ; Human . PubMed: 19638587
  • Joh K  et al. Antisense transcription occurs at the promoter of a mouse imprinted gene, commd1, on the repressed paternal allele. J Biochem 146:771-4 (2009). PubMed: 19762339
  • Yabuki M  et al. E2A acts in cis in G1 phase of cell cycle to promote Ig gene diversification. J Immunol 182:408-15 (2009). ICC/IF . PubMed: 19109172
  • Saramäki A  et al. Cyclical Chromatin Looping and Transcription Factor Association on the Regulatory Regions of the p21 (CDKN1A) Gene in Response to 1{alpha},25-Dihydroxyvitamin D3. J Biol Chem 284:8073-82 (2009). ChIP ; Human . PubMed: 19122196
  • Shandilya J  et al. Acetylated NPM1 localizes in the nucleoplasm and regulates transcriptional activation of genes implicated in oral cancer manifestation. Mol Cell Biol 29:5115-27 (2009). ChIP ; Human . PubMed: 19581289
  • Hargreaves DC  et al. Control of inducible gene expression by signal-dependent transcriptional elongation. Cell 138:129-45 (2009). ChIP ; Mouse . PubMed: 19596240
  • Fullwood MJ  et al. An oestrogen-receptor-alpha-bound human chromatin interactome. Nature 462:58-64 (2009). CHIPseq ; Human . PubMed: 19890323
  • Mueller D  et al. Misguided transcriptional elongation causes mixed lineage leukemia. PLoS Biol 7:e1000249 (2009). ChIP ; Mouse . PubMed: 19956800
  • Conroy A  et al. SNS-032 is a potent and selective CDK 2, 7 and 9 inhibitor that drives target modulation in patient samples. Cancer Chemother Pharmacol 64:723-32 (2009). PubMed: 19169685
  • Cao D  et al. Combined proteomic-RNAi screen for host factors involved in human hepatitis delta virus replication. RNA 15:1971-9 (2009). PubMed: 19776158
  • Hu P  et al. Estrogen induces ERRalpha gene expression and chromatin structural. J Biol Chem : (2008). WB ; Human . PubMed: 18174157
  • Pan YF  et al. Regulation of estrogen receptor-mediated long range transcription via evolutionarily conserved distal response elements. J Biol Chem 283:32977-88 (2008). Human . PubMed: 18728018
  • Yochum GS  et al. A genome-wide screen for beta-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression. Mol Cell Biol 28:7368-79 (2008). ChIP ; Human . PubMed: 18852287
  • Hoivik EA  et al. Deoxyribonucleic acid methylation controls cell type-specific expression of steroidogenic factor 1. Endocrinology 149:5599-609 (2008). ChIP ; Human, Mouse . PubMed: 18653709
  • Schones DE  et al. Dynamic regulation of nucleosome positioning in the human genome. Cell 132:887-98 (2008). CHIPseq ; Human . PubMed: 18329373
  • Metzger E  et al. Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulation. Nat Cell Biol 10:53-60 (2008). ChIP ; Human . PubMed: 18066052
  • Racanelli AC  et al. A mouse gene that coordinates epigenetic controls and transcriptional interference to achieve tissue-specific expression. Mol Cell Biol 28:836-48 (2008). ChIP ; Mouse . PubMed: 17998333
  • Wagschal A  et al. G9a histone methyltransferase contributes to imprinting in the mouse placenta. Mol Cell Biol 28:1104-13 (2008). ChIP ; Mouse . PubMed: 18039842
  • Moldón A  et al. Promoter-driven splicing regulation in fission yeast. Nature 455:997-1000 (2008). ChIP ; Schizosaccharomyces pombe . PubMed: 18815595
  • Houwing S  et al. Zili is required for germ cell differentiation and meiosis in zebrafish. EMBO J 27:2702-11 (2008). IHC-Fr ; Zebrafish . PubMed: 18833190
  • Qin HR  et al. Wwox suppresses prostate cancer cell growth through modulation of ErbB2-mediated androgen receptor signaling. Mol Cancer Res 5:957-65 (2007). PubMed: 17704139
  • Dahlin A  et al. Expression and immunolocalization of the plasma membrane monoamine transporter in the brain. Neuroscience 146:1193-211 (2007). PubMed: 17408864
  • Hoogenkamp M  et al. The Pu.1 locus is differentially regulated at the level of chromatin structure and noncoding transcription by alternate mechanisms at distinct developmental stages of hematopoiesis. Mol Cell Biol 27:7425-38 (2007). PubMed: 17785440

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