Anti-RNA Polymerase II p14.5 antibody (ab57305)

Overview

  • Product nameAnti-RNA Polymerase II p14.5 antibody
    See all RNA Polymerase II p14.5 primary antibodies
  • Description
    Mouse monoclonal to RNA Polymerase II p14.5
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: PKEDKENRIL LYACRNCDYQ QEADNSCIYV NKITHEVDEL TQIIADVSQD PTLPRTEDHP CQKCGHKEAV FFQSHSARAE DAMRLYYVCT APHCGHRWTE , corresponding to amino acids 26-126 of Human RNA Polymerase II p14.5

Properties

Applications

Our Abpromise guarantee covers the use of ab57305 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionDNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template.
    • Sequence similaritiesBelongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
      Contains 1 TFIIS-type zinc finger.
    • Post-translational
      modifications
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • DNA directed RNA polymerase II 14.5 kDa polypeptide antibody
      • DNA directed RNA polymerase II polypeptide I antibody
      • DNA directed RNA polymerase II subunit I antibody
      • DNA directed RNA polymerase II subunit RPB9 antibody
      • DNA-directed RNA polymerase II subunit I antibody
      • DNA-directed RNA polymerase II subunit RPB9 antibody
      • hRPB14.5 antibody
      • POLR2I antibody
      • Polymerase (RNA) II (DNA directed) polypeptide I 14.5kDa antibody
      • RNA polymerase II 14.5 kDa subunit antibody
      • RNA polymerase II subunit B9 antibody
      • RPB14.5 antibody
      • RPB9 antibody
      • RPB9_HUMAN antibody
      see all

    Anti-RNA Polymerase II p14.5 antibody images

    • Western blot against tagged recombinant protein immunogen using ab57305 RNA Polymerase II p14.5 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    References for Anti-RNA Polymerase II p14.5 antibody (ab57305)

    ab57305 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you very much for your interest in our antibodies.

    Unfortunately we do not have aliquots of our products and I can therefore not send you some small vials. However I can provide you with our testing offer: I can offer a discount off a f...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"