Overview

  • Product name
    Anti-RNASE6 antibody
  • Description
    Rabbit polyclonal to RNASE6
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 25-144 of Human RNASE6 (Q93091).

  • Positive control
    • Human Liver tissue

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab121111 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Use buffer at pH 6 for antigen retrieval.

Target

  • Function
    May have a role in host defense.
  • Tissue specificity
    Strong expression in lung, followed by heart, placenta, kidney, pancreas, liver, brain and skeletal muscle. Also expressed in monocytes and neutrophils.
  • Sequence similarities
    Belongs to the pancreatic ribonuclease family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Ribonuclease K6 antibody
    • RNAS6_HUMAN antibody
    • RNase K6 antibody
    • RNASE6 antibody

Images

  • Immunohistochemical staining of Human liver shows moderate cytoplasmic positivity in hepatocytes, ab121111 used at a dilution of 1/25.

References

This product has been referenced in:
  • Becknell B  et al. Ribonucleases 6 and 7 have antimicrobial function in the human and murine urinary tract. Kidney Int N/A:N/A (2014). Read more (PubMed: 25075772) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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