Overview

  • Product name
  • Description
    Rabbit polyclonal to RND1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 183-232 (ASMLCLNKPS PLPQKSPVRS LSKRLLHLPS RSELISSTFK KEKAKSCSIM) of Human RND1 (NP_055285).

  • Positive control
    • THP1 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab118299 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 26 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments.
  • Tissue specificity
    Mostly expressed in brain and liver.
  • Sequence similarities
    Belongs to the small GTPase superfamily. Rho family.
  • Cellular localization
    Cell membrane. Cytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARHS antibody
    • FLJ42294 antibody
    • GTP binding protein RHO6 antibody
    • Ras homolog gene family member S antibody
    • RHO 6 antibody
    • Rho family GTPase 1 antibody
    • Rho related GTP binding protein Rho6 antibody
    • RHO S antibody
    • Rho-related GTP-binding protein Rho6 antibody
    • RHO6 antibody
    • RHOS antibody
    • RND 1 antibody
    • Rnd1 antibody
    • RND1_HUMAN antibody
    see all

Images

  • Anti-RND1 antibody (ab118299) at 1 µg/ml + THP1 cell lysate at 10 µg

    Predicted band size : 26 kDa

References

ab118299 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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The immunogen of ab118299 has 90% sequence homology with mouse rnd1, this may be the candidate to try.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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