Overview

  • Product name
    Anti-RND3 antibody [4]
    See all RND3 primary antibodies
  • Description
    Mouse monoclonal [4] to RND3
  • Tested applications
    Suitable for: WB, ICC/IF, IHC-Frmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Purified recombinant full length RND3

  • Positive control
    • HMVEC total cell extract.
  • General notes


    Monoclonal antibodies specific for RhoE(Rnd3) are an important tool for studying cell motility and cytoskeleton organization.

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by July 2018 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause. 

Properties

Applications

Our Abpromise guarantee covers the use of ab50316 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 4 - 8 µg/ml. Predicted molecular weight: 27 kDa.
ICC/IF 1/200. PubMed: 19349584
IHC-Fr 1/200. PubMed: 19349584

Target

  • Function
    Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Belongs to the small GTPase superfamily. Rho family.
  • Cellular localization
    Golgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARHE antibody
    • memB antibody
    • Protein MemB antibody
    • Ras homolog gene family member E antibody
    • Rho family GTPase 3 antibody
    • Rho-related GTP-binding protein Rho8 antibody
    • Rho-related GTP-binding protein RhoE antibody
    • Rho8 antibody
    • RhoE antibody
    • Rnd3 antibody
    • RND3_HUMAN antibody
    • Small GTP binding protein Rho8 antibody
    see all

References

This product has been referenced in:
  • Pacary E  et al. Rnd3 coordinates early steps of cortical neurogenesis through actin-dependent and -independent mechanisms. Nat Commun 4:1635 (2013). IHC-Fr ; Mouse . Read more (PubMed: 23535656) »
  • Pacary E  et al. Proneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signaling. Neuron 69:1069-84 (2011). ICC/IF ; Mouse . Read more (PubMed: 21435554) »

See all 4 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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