Anti-RNF111 antibody - N-terminal (ab174624)

Overview

  • Product name
    Anti-RNF111 antibody - N-terminal
    See all RNF111 primary antibodies
  • Description
    Rabbit polyclonal to RNF111 - N-terminal
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human RNF111 aa 208-237 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q6ZNA4

  • Positive control
    • A549 cell line lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab174624 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 109 kDa.

Target

  • Function
    Acts in the NODAL pathway of mesoderm patterning during embryonic development. Acts downstream AXIN1 as an E3 ubiquitin-protein ligase which promotes the ubiquitination of inhibitory SMADs such as SMAD7, induces their proteasomal degradation and thereby enhances the transcriptional activity of TGF-beta and BMP. Activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation.
  • Tissue specificity
    Broadly expressed.
  • Pathway
    Protein modification; protein ubiquitination.
  • Sequence similarities
    Contains 1 RING-type zinc finger.
  • Cellular localization
    Nucleus. Cytoplasm. Upon TGF-beta treatment, translocates from nucleus to cytosol.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARK antibody
    • Arkadia antibody
    • DKFZp313E0731 antibody
    • DKFZp686H1966 antibody
    • DKFZp761D081 antibody
    • E3 ubiquitin protein ligase Arkadia antibody
    • E3 ubiquitin-protein ligase Arkadia antibody
    • FLJ38008 antibody
    • RING finger protein 111 antibody
    • RN111_HUMAN antibody
    • RNF 111 antibody
    • RNF111 antibody
    see all

Images

  • Anti-RNF111 antibody - N-terminal (ab174624) at 1/100 dilution + A549 cell line lysates at 35 µg

    Predicted band size : 109 kDa

References

ab174624 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab174624.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up