Application notesThis antibody gave a positive result in ELISA against the immunizing peptide. Antibody detection limit dilution 1:8,000.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceRNF125 is a novel E3 ubiquitin ligase that is expressed in CD4 and CD8 positive T cells and contains an N-terminal RING finger domain. It may function as a positive regulator in the T-cell receptor signaling pathway. E3 ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins.