Overview

  • Product nameAnti-RNF138 antibody
    See all RNF138 primary antibodies
  • Description
    Mouse monoclonal to RNF138
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: GAHCPLCRGN VTRRERACPE RALDLENIMR KFSGSCRCCA KQIKFYRMRH HYKSCKKYQD EYGVSSIIPN FQISQDSVGN SNRSETSTSD NTETYQENTS , corresponding to amino acids 51-151 of Human RNF138

Properties

Applications

Our Abpromise guarantee covers the use of ab57092 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000.

Target

  • FunctionE3 ubiquitin-protein ligase. Together with NLK, involved in the ubiquitination and degradation of TCF/LEF. Also exhibits auto-ubiquitination activity in combination with UBE2K. May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway.
  • PathwayProtein modification; protein ubiquitination.
  • Sequence similaritiesContains 1 RING-type zinc finger.
  • DomainThe RING-type zinc finger domain mediates binding to an E2 ubiquitin-conjugating enzyme.
  • Post-translational
    modifications
    Auto-ubiquitinated.
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Information by UniProt
  • Database links
  • Alternative names
    • E3 ubiquitin protein ligase RNF138 antibody
    • E3 ubiquitin-protein ligase RNF138 antibody
    • hNARF antibody
    • HSD 4 antibody
    • HSD4 antibody
    • MGC8758 antibody
    • NARF antibody
    • Nemo like kinase associated RING finger protein antibody
    • Nemo-like kinase-associated RING finger protein antibody
    • NLK associated RING finger protein antibody
    • NLK-associated RING finger protein antibody
    • RING finger protein 138 antibody
    • ring finger protein 138, E3 ubiquitin protein ligase antibody
    • RN138_HUMAN antibody
    • Rnf138 antibody
    • STRIN antibody
    see all

Anti-RNF138 antibody images

  • Western blot against tagged recombinant protein immunogen using ab57092 RNF138 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

References for Anti-RNF138 antibody (ab57092)

ab57092 has not yet been referenced specifically in any publications.

Product Wall

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