Overview

  • Product nameAnti-RNF14 antibody
    See all RNF14 primary antibodies
  • Description
    Mouse monoclonal to RNF14
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment: LFLCSICFCE KLGSECMYFL ECRHVYCKAC LKDYFEIQIR DGQVQCLNCP EPKCPSVATP GQVKELVEAE LFARYDRLLL QSSLDLMADV VYCPRPCCQL , corresponding to amino acids 217-317 of Human RNF14

Properties

Applications

Our Abpromise guarantee covers the use of ab56605 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMight act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription.
    • Tissue specificityWidely expressed.
    • PathwayProtein modification; protein ubiquitination.
    • Sequence similaritiesBelongs to the RBR family. RNF14 subfamily.
      Contains 1 IBR-type zinc finger.
      Contains 2 RING-type zinc fingers.
      Contains 1 RWD domain.
    • DomainThe N-terminal destruction box (D-box) acts as a recognition signal for degradation via the ubiquitin-proteasome pathway.
      The RING-type zinc finger is essential for the interaction with UBE2E2.
    • Post-translational
      modifications
      RING-type zinc finger-dependent and UBE2E2-dependent autoubiquitination.
    • Cellular localizationCytoplasm. Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • Androgen receptor associated protein 54 antibody
      • Androgen receptor-associated protein 54 antibody
      • ARA 54 antibody
      • ARA54 antibody
      • E3 ubiquitin protein ligase RNF14 antibody
      • E3 ubiquitin-protein ligase RNF14 antibody
      • FLJ26004 antibody
      • HFB 30 antibody
      • HFB30 antibody
      • HRIHFB2038 antibody
      • RING finger protein 14 antibody
      • RNF 14 antibody
      • Rnf14 antibody
      • RNF14_HUMAN antibody
      • TRIAD 2 antibody
      • TRIAD2 antibody
      • Triad2 protein antibody
      see all

    Anti-RNF14 antibody images

    • Western blot against tagged recombinant protein immunogen using ab56605 RNF14 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    References for Anti-RNF14 antibody (ab56605)

    This product has been referenced in:
    • Grimont A  et al. Mapping of sex hormone receptors and their modulators along the nephron of male and female mice. FEBS Lett 583:1644-8 (2009). WB ; Mouse . Read more (PubMed: 19401201) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"