Overview

  • Product name
  • Description
    Rabbit polyclonal to RNF167
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within intracellular amino acids 179-228 (GIVGLLVLAM GAVMIARCIQ HRKRLQRNRL TKEQLKQIPT HDYQKGDQYD) of Human RNF167 (NP_056343).

  • Positive control
    • HeLa Cell Lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab105568 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 38 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition.
  • Tissue specificity
    Strongly expressed in the kidney and liver (at protein level).
  • Pathway
    Protein modification; protein ubiquitination.
  • Sequence similarities
    Contains 1 PA (protease associated) domain.
    Contains 1 RING-type zinc finger.
  • Post-translational
    modifications
    Auto-ubiquitinated in vitro in the presence of UBE2D1 and UBE2E1.
  • Cellular localization
    Endomembrane system. Targeted to cytoplasmic membranes.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5730408C10Rik antibody
    • E3 ubiquitin-protein ligase RNF167 antibody
    • LP2254 antibody
    • RING finger protein 167 antibody
    • RING105 antibody
    • RN167_HUMAN antibody
    • RNF167 antibody
    see all

Images

  • Anti-RNF167 antibody (ab105568) at 1 µg/ml + HeLa Cell Lysate at 10 µg

    Predicted band size : 38 kDa

References

ab105568 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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