Overview

  • Product nameAnti-RNF70 antibody
  • Description
    Mouse monoclonal to RNF70
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment: DSESSGTNLN IDNEDYSRYP PREYRASGSR RGMAYGHIDS YGADDSEEEG AGPVERPPVR GKTGKFKDDK LYDPEKGARS LAGPPPHFSS FSRDVREERD , corresponding to amino acids 81-181 of Human RNF70

Properties

Applications

Our Abpromise guarantee covers the use of ab56395 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionHas E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome (By similarity). May be involved in protein sorting.
    • Tissue specificityExpressed in various regions of the brain including the cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Highest levels in the cerebral cortex.
    • Sequence similaritiesContains 1 RING-type zinc finger.
    • DomainThe RING-type zinc finger domain interacts with an ubiquitin-conjugating enzyme (E2) and facilitates ubiquitination.
    • Post-translational
      modifications
      Substrate for E2-dependent ubiquitination.
    • Information by UniProt
    • Database links
    • Alternative names
      • E3 ubiquitin-protein ligase Praja 1 antibody
      • E3 ubiquitin-protein ligase Praja-1 antibody
      • PJA1 antibody
      • PJA1_HUMAN antibody
      • PRAJA 1 antibody
      • Praja ring finger 1 antibody
      • Praja1 antibody
      • RING finger protein 70 antibody
      • RNF 70 antibody
      • RP23-414J22.4 antibody
      see all

    Anti-RNF70 antibody images

    • Western blot against tagged recombinant protein immunogen using ab56395 RNF70 antibody at 1ug/ml. Predicted band size of the tagged immunogen is 37 kDa. The immunogen alone is 11.2 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    References for Anti-RNF70 antibody (ab56395)

    ab56395 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab56395.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"