Anti-RON (phospho Y1353) antibody [EPR5598] (ab124671)

Overview

  • Product nameAnti-RON (phospho Y1353) antibody [EPR5598]
    See all RON primary antibodies
  • Description
    Rabbit monoclonal [EPR5598] to RON (phospho Y1353)
  • SpecificityOnly detects RON phosphorylated at Tyrosine 1353.
  • Tested applicationsSuitable for: WB, IP, ICC/IFmore details
    Unsuitable for: Flow Cyt or IHC-P
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A phospho specific C-Terminal peptide corresponding to residues surrounding Tyrosine 1353 of Human RON.

  • Positive control
    • A431 cell lysates treated with pervanadate; A431 cells.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

Applications

Our Abpromise guarantee covers the use of ab124671 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50000 - 1/200000. Detects a band of approximately 180 kDa (predicted molecular weight: 152 kDa).
IP 1/10 - 1/100.
ICC/IF 1/500 - 1/1000.
  • Application notesIs unsuitable for Flow Cyt or IHC-P.
  • Target

    • FunctionReceptor for macrophage stimulating protein (MSP). Has a tyrosine-protein kinase activity.
    • Tissue specificityKeratinocytes and lung.
    • Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family.
      Contains 3 IPT/TIG domains.
      Contains 1 protein kinase domain.
      Contains 1 Sema domain.
    • Post-translational
      modifications
      Proteolytic processing yields the two subunits.
      Phosphorylated in response to ligand binding.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • c met related tyrosine kinase antibody
      • CD136 antibody
      • CD136 antigen antibody
      • CDw136 antibody
      • Macrophage stimulating 1 receptor (c met related tyrosine kinase) antibody
      • Macrophage stimulating 1 receptor antibody
      • Macrophage stimulating protein receptor alpha chain antibody
      • MACROPHAGE STIMULATING PROTEIN RECEPTOR antibody
      • Macrophage stimulating protein receptor beta chain antibody
      • Macrophage-Stimulating 1 Receptor (MST1R) antibody
      • Macrophage-stimulating protein receptor beta chain antibody
      • MSP receptor antibody
      • Mst1r antibody
      • MST1R variant RON30 antibody
      • MST1R variant RON62 antibody
      • p185 RON antibody
      • p185-Ron antibody
      • Protein-tyrosine kinase 8 antibody
      • PTK 8 antibody
      • ptk8 antibody
      • PTK8 protein tyrosine kinase 8 antibody
      • Recepteur d’origine nantais (RON) antibody
      • RON antibody
      • RON protein tyrosine kinase antibody
      • RON variant E2E3 antibody
      • RON_HUMAN antibody
      • Soluble RON variant 1 antibody
      • Soluble RON variant 2 antibody
      • Soluble RON variant 3 antibody
      • Soluble RON variant 4 antibody
      • Stem cell derived tyrosine kinase antibody
      see all

    Anti-RON (phospho Y1353) antibody [EPR5598] images

    • All lanes : Anti-RON (phospho Y1353) antibody [EPR5598] (ab124671) at 1/50000 dilution

      Lane 1 : A431 cell lysates, untreated
      Lane 2 : A431 cell lysates, treated with pervanadate


      Predicted band size : 152 kDa
    • ab124671, at 1/500 dilution, staining RON in A431 cells by Immunofluorescence.
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References for Anti-RON (phospho Y1353) antibody [EPR5598] (ab124671)

    ab124671 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"