Overview

  • Product name
    Ropivacaine hydrochloride
  • Description
    Reversible sodium ion influx inhibitor. Long-acting amide local anaesthetic agent.
  • Biological description
    Reversible sodium ion influx inhibitor. Long-acting amide local anesthetic agent. Blocks impulse conduction in nerve fibers. Less lipophilic than bupivacaine (ab142490, ab143182) so shows more sensory nerve selectivity. Shows anesthetic effects in vivo.

Properties

  • Chemical name
    (2S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide hydrochloride
  • Molecular weight
    310.86
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C17H26N2O.HCl
  • CAS Number
    132112-35-7
  • PubChem identifier
    175804
  • Storage instructions
    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in water to 100 mM and in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    CCCN1CCCC[C@H]1C(=O)NC2=C(C=CC=C2C)C.Cl
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:
  • Uemura Y  et al. Effects of various antiepileptics used to alleviate neuropathic pain on compound action potential in frog sciatic nerves: comparison with those of local anesthetics. Biomed Res Int 2014:540238 (2014). Read more (PubMed: 24707490) »
  • Mantha VR  et al. Nanoanesthesia: a novel, intravenous approach to ankle block in the rat by magnet-directed concentration of ropivacaine-associated nanoparticles. Anesth Analg 118:1355-62 (2014). Read more (PubMed: 24722259) »
  • Zhang L  et al. Different effects of local anesthetics on extracellular signal-regulated kinase phosphorylation in rat dorsal horn neurons. Eur J Pharmacol 734:132-6 (2014). Read more (PubMed: 24726558) »

See 0 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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