Anti-Rotavirus antibody (FITC) (ab31435)

Overview

  • Product nameAnti-Rotavirus antibody (FITC)
    See all Rotavirus primary antibodies
  • Description
    Goat polyclonal to Rotavirus (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • Tested applicationsSuitable for: ICC/IF, ELISAmore details
  • Species reactivity
    Rotavirus (whole virus) 100%
  • Immunogen

    Tissue/ cell preparation: Bovine rotavirus (whole virus).

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C.
  • Storage bufferPreservative: 0.1% Sodium Azide.
    Constituents: 1% BSA, PBS, pH 7.2.
  • Concentration information loading...
  • PurityIgG fraction
  • Purification notesAmmonium sulfate fractionation and ion-exchange chromatography.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab31435 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/250. Acetone fixed.
ELISA Use at an assay dependent dilution.

Target

  • RelevanceRotaviruses, members of the family Reoviridae, are a major cause of diarrhoea in young mammals. Rotavirus infections also result in economic losses in agriculture due to diarrhoea in calf, pig, sheep, and poultry rearing. Diarrhoea (or scours) due to the rotavirus Nebraska Calf Diarrhea Virus can affect calves up to 30 days of age or older. Diarrhoea begins 2 to 3 days after exposure. Diagnosis is by history, lesions (ulcers on the tongue, lips, and mouth) and diagnostic laboratory tests. Mortality rates may be as high as 50 percent, depending on the secondary bacteria present. Human rotaviruses, the major aetiological agents of severe infantile diarrhoea worldwide, display surprisingly diverse and complex serotypic specificities. Rotaviruses are 70 nm, non enveloped viruses comprised of a triple layered protein capsid; Outer capsid proteins are VP4 and VP7, Inner capsid -VP6 and Core -VP2. The immunity acquired from exposure to rotavirus appears to be type specific following initial infection; therefore, multiple serotypes of rotavirus mean multiple opportunities for infection. The combination of animal reservoirs for the virus and rotavirus gene reassortment provides the potential for dramatic genetic shifts (similar to influenza virus) which could give rise to altered host ranges and viral virulence.
  • Alternative names
    • Major inner capsid protein VP6 antibody
    • NSP4 antibody
    • VP6 antibody

References for Anti-Rotavirus antibody (FITC) (ab31435)

ab31435 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us.

The immunogen for this antibody is Nebraska Calf Diarrhea Virus (whole virus).



The antibody recognizes rotavirus and is specific for ICPs and late structural (virion) antigens. No further epitope...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"