Overview

  • Product name
    Anti-Rotavirus NCDV antibody (Biotin)
  • Description
    Goat polyclonal to Rotavirus NCDV (Biotin)
  • Conjugation
    Biotin
  • Specificity
    ab69560 reacts with Rotavirus NCDV in viral and infected bovine samples.
  • Tested applications
    Suitable for: WB, ELISA, IHC-Fr, ICC/IFmore details
  • Species reactivity
    Reacts with Rotavirus NCDV (Nebraska calf diarrhea virus).
  • Immunogen

    Rotavirus (NCDV) ICP + virions.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.1% Sodium Azide
    Constituents: 0.01M PBS
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab69560 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 1 kDa.
ELISA Use at an assay dependent dilution.
IHC-Fr Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.

Target

  • Relevance
    Rotaviruses, members of the family Reoviridae, are a major cause of diarrhoea in young mammals. Rotavirus infections also result in economic losses in agriculture due to diarrhoea in calf, pig, sheep, and poultry rearing. Nebraska Calf Diarrhea Virus (NCVD) can affect calves up to 30 days of age or older. Diarrhoea begins 2 to 3 days after exposure. Diagnosis is by history, lesions (ulcers on the tongue, lips, and mouth) and diagnostic laboratory tests. Mortality rates may be as high as 50 percent, depending on the secondary bacteria present. Human rotaviruses, the major aetiological agents of severe infantile diarrhoea worldwide, display surprisingly diverse and complex serotypic specificities. Rotaviruses are 70 nm, non enveloped viruses comprised of a triple layered protein capsid; Outer capsid proteins are VP4 and VP7, Inner capsid -VP6 and Core -VP2. The immunity acquired from exposure to rotavirus appears to be type specific following initial infection; therefore, multiple serotypes of rotavirus mean multiple opportunities for infection. The combination of animal reservoirs for the virus and rotavirus gene reassortment provides the potential for dramatic genetic shifts (similar to influenza virus) which could give rise to altered host ranges and viral virulence.
  • Alternative names
    • Nebraska calf diarrhea virus antibody
    • Rotavirus antibody

References for Anti-Rotavirus NCDV antibody (Biotin) (ab69560)

This product has been referenced in:
  • Jere KC  et al. Chimaeric virus-like particles derived from consensus genome sequences of human rotavirus strains co-circulating in Africa. PLoS One 9:e105167 (2014). Read more (PubMed: 25268783) »

See 1 Publication for this product

Product Wall

Thank you for contacting Abcam.

Both ab69560 and ab10012 are in stock at the moment, whilst the other 2 have a delay of 1-2 weeks. You can find the most up-to date information using the links:

http://www.abcam.com/Rotavirus-NCDV-antib...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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