Overview

  • Product name
    Rotigotine hydrochloride
  • Description
    Dopamine receptor agonist
  • Alternative names
    • N 0923
  • Biological description
    Dopamine receptor agonist. High affinity for D1, D2 and D3 receptors (Ki values are 83, 13 and 0.71 nM, respectively). Shows significant affinity at α2B and 5-HT1A receptors (Ki values are 27 and 30 nM, respectively). Exhibits anti-Parkinsonian and antidepressant activity.
  • Purity
    > 99%

Properties

References

This product has been referenced in:
  • Scheller D  et al. The in vitro receptor profile of rotigotine: a new agent for the treatment of Parkinson's disease. Naunyn Schmiedebergs Arch Pharmacol 379:73-86 (2009). Read more (PubMed: 18704368) »
  • Scheller D  et al. Neuroprotective effects of rotigotine in the acute MPTP-lesioned mouse model of Parkinson's disease. Neurosci Lett 432:30-4 (2008). Read more (PubMed: 18162314) »
  • Bertaina-Anglade V  et al. Antidepressant properties of rotigotine in experimental models of depression. Eur J Pharmacol 548:106-14 (2006). Read more (PubMed: 16959244) »

See 0 Publications for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab120601.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

Sign up