Overview

  • Product name
  • Description
    Rabbit polyclonal to RP105
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 195-503 of Human RP105 (Q99467).

  • Positive control
    • HL60 whole cell lysate; CL15 xenograft tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab126267 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 74 kDa.
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells.
  • Tissue specificity
    Expressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells.
  • Sequence similarities
    Belongs to the Toll-like receptor family.
    Contains 19 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD180 antibody
    • CD180 antigen antibody
    • CD180_HUMAN antibody
    • F630107B15 antibody
    • LY64 antibody
    • Ly78 antibody
    • Lymphocyte antigen 64 antibody
    • lymphocyte antigen 64 radioprotective 105kDa antibody
    • lymphocyte antigen-64, radioprotective, 105kDa antibody
    • MGC126233 antibody
    • MGC126234 antibody
    • Radioprotective 105 kDa protein antibody
    • RP105 antibody
    see all

Images

  • Anti-RP105 antibody (ab126267) at 1/1000 dilution + HL60 whole cell lysate at 30 µg

    Predicted band size : 74 kDa
  • ab126267, at 1/500 dilution, staining RP105 in CL15 xenograft tissue by Immunohistochemistry.

References

ab126267 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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