Overview

  • Product name
    Anti-RP105 antibody [MHR73]
    See all RP105 primary antibodies
  • Description
    Mouse monoclonal [MHR73] to RP105
  • Tested applications
    Suitable for: IHC-Fr, Flow Cyt, IPmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Mouse B-cell line M12HRP expressing human RP105 complexed with mouse MD1 (see Miura Y et al).

Properties

Applications

Our Abpromise guarantee covers the use of ab11880 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr
Flow Cyt
IP
  • Application notes
    Flow Cyt: Use at an assay dependent dilution.
    IHC-Fr: Use at an assay dependent dilution.
    IP: Use at an assay dependent dilution.

    This antibody is also useful for in vitro functional studies.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells.
    • Tissue specificity
      Expressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells.
    • Sequence similarities
      Belongs to the Toll-like receptor family.
      Contains 19 LRR (leucine-rich) repeats.
      Contains 1 LRRCT domain.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD180 antibody
      • CD180 antigen antibody
      • CD180_HUMAN antibody
      • F630107B15 antibody
      • LY64 antibody
      • Ly78 antibody
      • Lymphocyte antigen 64 antibody
      • lymphocyte antigen 64 radioprotective 105kDa antibody
      • lymphocyte antigen-64, radioprotective, 105kDa antibody
      • MGC126233 antibody
      • MGC126234 antibody
      • Radioprotective 105 kDa protein antibody
      • RP105 antibody
      see all

    References

    This product has been referenced in:

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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