• Product name
  • Description
    Rabbit polyclonal to RP2
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within internal amino acids 300-349 of Human RP2 (NP_008846).

  • Positive control
    • human Fetal muscle lysate


  • Form
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
  • Isotype
  • Research areas


Our Abpromise guarantee covers the use of ab98353 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 40 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • Relevance
    Function: Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119 (or UNC119B). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins. Tissue specificity: Ubiquitous. Expressed in the rod and cone photoreceptors, extending from the tips of the outer segment (OS) through the inner segment (IS) and outer nuclear layer (ONL) and into the synaptic terminals of the outer plexiform layer (ONL). Also detected in the bipolar, horizontal and amacrine cells in the inner nuclear layer (INL), extending to the inner plexiform layer (IPL) and though the ganglion cell layer (GCL) and into the nerve fiber layer (NFL) (at protein level). Disease: Retinitis pigmentosa 2 Similarity: Belongs to the TBCC family. Contains 1 C-CAP/cofactor C-like domain. PTM: Myristoylated on Gly-2; which may be required for membrane targeting. Palmitoylated on Cys-3; which may be required for plasma membrane targeting (Probable). Mutation of Cys-3 targets the protein to internal membranes.
  • Cellular localization
    Cell membrane; Lipid-anchor; Cytoplasmic side
  • Database links
  • Alternative names
    • DELXp11.3 antibody
    • KIAA0215 antibody
    • NM23 H10 antibody
    • NME10 antibody
    • Protein XRP2 antibody
    • Retinitis pigmentosa 2 (X linked recessive) antibody
    • Retinitis pigmentosa 2 antibody
    • RP 2 antibody
    • RP2 antibody
    • RP2 ARL3 GTPase activating protein antibody
    • TBCCD 2 antibody
    • TBCCD2 antibody
    • XRP2 antibody
    • XRP2 protein antibody
    • XRP2_HUMAN antibody
    see all

Anti-RP2 antibody images

  • Anti-RP2 antibody (ab98353) at 1 µg/ml + Human fetal muscle lysate at 10 µg

    Predicted band size : 40 kDa
    Gel concentration: 12%
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human brain, cerebellum tissue labelling RP2 with ab98353 at 5µg/ml.

References for Anti-RP2 antibody (ab98353)

ab98353 has not yet been referenced specifically in any publications.

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