• Product nameAnti-RPGRIP1L antibody
    See all RPGRIP1L primary antibodies
  • Description
    Rabbit polyclonal to RPGRIP1L
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide selected from the N-terminal region of Human RPGRIP1L conjugated to KLH (NP_056087.2).

  • Positive control
    • 293 cell line lysates.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab91467 is purified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab91467 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 151 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionNegatively regulates signaling through the G-protein coupled thromboxane A2 receptor (TBXA2R). May be involved in mechanisms like programmed cell death, craniofacial development, patterning of the limbs, and formation of the left-right axis (By similarity). Involved in the organization of apical junctions in kidney cells together with NPHP1 and NPHP4 (By similarity). Does not seem to be strictly required for ciliogenesis.
    • Tissue specificityUbiquitously expressed with relatively high level of expression in hypothalamus and islet. During early development, expressed in multiple organs including brain, eye, forelimb and kidney.
    • Involvement in diseaseCiliary dysfunction leads to a broad spectrum of disorders, collectively termed ciliopathies. Overlapping clinical features include retinal degeneration, renal cystic disease, skeletal abnormalities, fibrosis of various organ, and a complex range of anatomical and functional defects of the central and peripheral nervous system. The ciliopathy range of diseases includes Meckel-Gruber syndrome, Bardet-Biedl syndrome, Joubert syndrome, nephronophtisis, Senior-Loken syndrome, and Jeune asphyxiating thoracic dystrophy among others. Single-locus allelism is insufficient to explain the variable penetrance and expressivity of such disorders, leading to the suggestion that variations across multiple sites of the ciliary proteome, including RPGRIP1L, influence the clinical outcome.
      Joubert syndrome 7
      Meckel syndrome 5
      COACH syndrome
    • Sequence similaritiesBelongs to the RPGRIP1 family.
      Contains 2 C2 domains.
    • Cellular localizationCytoplasm. Cytoplasm > cytoskeleton > cilium basal body. Cytoplasm > cytoskeleton > cilium axoneme. Cytoplasm > cytoskeleton > microtubule organizing center > centrosome. Cell junction > tight junction. In cultured renal cells, it localizes diffusely in the cytoplasm but, as cells approach confluence, it accumulates to basolateral tight junctions.
    • Information by UniProt
    • Database links
    • Alternative names
      • CORS 3 antibody
      • CORS3 antibody
      • Fantom antibody
      • FTM antibody
      • FTM_HUMAN antibody
      • JBTS 1 antibody
      • JBTS 7 antibody
      • JBTS1 antibody
      • JBTS7 antibody
      • Joubert syndrome 1 antibody
      • Joubert syndrome 7 antibody
      • Meckel syndrome, type 1 antibody
      • Meckel syndrome, type 5 antibody
      • MKS 5 antibody
      • MKS5 antibody
      • Nephrocystin-8 antibody
      • NPHP 8 antibody
      • NPHP8 antibody
      • Protein fantom antibody
      • Retinitis pigmentosa GTPase regulator interacting protein 1 like antibody
      • RPGR interacting protein 1 like protein antibody
      • RPGR-interacting protein 1-like protein antibody
      • RPGRIP1 like protein antibody
      • RPGRIP1-like protein antibody
      • Rpgrip1l antibody
      see all

    Anti-RPGRIP1L antibody images

    • Anti-RPGRIP1L antibody (ab91467) at 1/100 dilution + 293 cell line lysates at 35 µg

      Predicted band size : 151 kDa

    References for Anti-RPGRIP1L antibody (ab91467)

    ab91467 has not yet been referenced specifically in any publications.

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