Overview

  • Product name
    Anti-RPH3AL antibody
  • Description
    Rabbit polyclonal to RPH3AL
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 211-241 of Human RPH3AL (NP_008918.1), conjugated to KLH.

  • Positive control
    • K562 cell line lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab108048 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 34 kDa.

Target

  • Function
    Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells.
  • Tissue specificity
    Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells.
  • Sequence similarities
    Contains 1 FYVE-type zinc finger.
    Contains 1 RabBD (Rab-binding) domain.
  • Domain
    The N-terminus of the RabBD domain is necessary and sufficient for interaction with RAB27A.
  • Cellular localization
    Cytoplasm. Cytoplasmic vesicle > secretory vesicle membrane. Recruited to the vesicle membrane in a GTP-and RAB3B-dependent manner in epithelial cells.
  • Information by UniProt
  • Database links
  • Alternative names
    • Gm1753 antibody
    • No C2 domains protein antibody
    • Noc2 antibody
    • Rab effector Noc2 antibody
    • Rabphilin 3A-like (without C2 domains) antibody
    • Rabphilin 3A-like antibody
    • Rabphilin-3A-like protein antibody
    • RPH3AL antibody
    • RPH3L_HUMAN antibody
    see all

Images

  • Anti-RPH3AL antibody (ab108048) at 1/100 dilution + K562 cell line lysates at 35 µg

    Predicted band size : 34 kDa

References

ab108048 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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