Anti-RPS6KC1 antibody - N-terminal (ab170772)

Overview

  • Product name
    Anti-RPS6KC1 antibody - N-terminal
    See all RPS6KC1 primary antibodies
  • Description
    Rabbit polyclonal to RPS6KC1 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human RPS6KC1 aa 19-47 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q96S38

  • Positive control
    • Human skeletal muscle tissue; Mouse liver tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab170772 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/500. Predicted molecular weight: 119 kDa.

Target

  • Function
    May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell.
  • Tissue specificity
    Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon.
  • Sequence similarities
    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily.
    Contains 1 MIT domain.
    Contains 2 protein kinase domains.
    Contains 1 PX (phox homology) domain.
  • Domain
    The first protein kinase domain appears to be a pseudokinase domain as it does not contain the classical characteristics, such as the ATP-binding motif, ATP-binding site and active site.
  • Cellular localization
    Cytoplasm. Membrane. Also found in some small dot-like or ring-shaped early endosome structures.
  • Information by UniProt
  • Database links
  • Alternative names
    • 52 kDa ribosomal protein S6 kinase antibody
    • humS6PKh1 antibody
    • KS6C1_HUMAN antibody
    • Ribosomal protein S6 kinase 52kD polypeptide 1 antibody
    • Ribosomal protein S6 kinase 52kDa polypeptide 1 antibody
    • Ribosomal protein S6 kinase C1 antibody
    • Ribosomal protein S6 kinase delta 1 antibody
    • Ribosomal protein S6 kinase delta-1 antibody
    • Ribosomal S6 kinase like protein with two PSK domains 118 kDa protein antibody
    • Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein antibody
    • RPK 118 antibody
    • RPK118 antibody
    • RPS6KC1 antibody
    • RSKL1 antibody
    • S6K-delta-1 antibody
    • S6PKh1 antibody
    • SPHK1 binding protein antibody
    • SPHK1-binding protein antibody
    see all

Images

  • Anti-RPS6KC1 antibody - N-terminal (ab170772) at 1/100 dilution + Mouse liver tissue lysate at 35 µg

    Predicted band size: 119 kDa

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skeletal muscle tissue labeling RPS6KC1 with ab170772 at 1/10 dilution followed by peroxidase conjugation of the secondary antibody and DAB staining.

References

ab170772 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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