Overview

  • Product nameAnti-RPT2 antibody
    See all RPT2 primary antibodies
  • Description
    Rabbit polyclonal to RPT2
  • Specificityab22679 reacts with 19S regulator ATPase subunit Rpt2p (Yta5).
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Saccharomyces cerevisiae
  • Immunogen

    Recombinant (His-tagged) fusion protein: MGQGVSSGQD KKKKKGSNQK PKYEPPVQSK FGRKKRKGGP ATAEKLPNIY PSTRCKLKLL RMERIKDHLL LEEEFVSNSE ILKPFEKKQE EEKKQLEEIR, corresponding to N terminal amino acids 1-100 of S. cerevisiae RPT2.

Properties

Applications

Our Abpromise guarantee covers the use of ab22679 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/10000 - 1/50000. Detects a band of approximately 48 kDa.
    Notes: Dilute to working strength with phosphate buffered saline pH 7.2-7.4 and 1% normal goat serum (if a goat anti-rabbit IgG linker antibody is to be used).

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceIn the yeast, S. cerevisiae, 12 different members of a novel gene family of putative ATPases have been identified and characterised. Due to their relationship with TBP-1, a human immunodeficiency tat-binding protein, they have been designated the YTA family (yeast tat-binding analogues). The most outstanding feature of the YTA proteins and their relatives is that they share a region of high similarity which extends to some 300 amino acids in length. The amino acid sequences preceding the region of high similarity are less well conserved but do contain similar structural domains, i.e. coil-coil propensities, leucine zipper-like structures. However, despite the highly conserved structural features among the YTA family, diverse functions have been assigned to the various family members. The putative gene products of YTA1, YTA2, YTA3 and YTA5 are all closely related to proteins known to be constituents of the human 26S proteasome. RPT2 (YTA5), of all members of the YTA family, shows the highest similarity with subunit 4 of the human 26S proteasome, and is presumed to be the true yeast homologue.
    • Cellular localizationCytoplasmic and Nuclear
    • Database links
      • Alternative names
        • 26S protease regulatory subunit 4 homolog antibody
        • P26s4 antibody
        • TAT binding homolog 5 antibody
        • YHS4 antibody
        • YTA5 antibody
        see all

      Anti-RPT2 antibody images

      References for Anti-RPT2 antibody (ab22679)

      ab22679 has not yet been referenced specifically in any publications.

      Product Wall

      There are currently no Abreviews or Questions for ab22679.
      Please use the links above to contact us or submit feedback about this product.

      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"