Overview

  • Product name
    Anti-RRAGB antibody
  • Description
    Rabbit polyclonal to RRAGB
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-374 of Human RRAGB (NP_057740.2).

  • Positive control
    • Human placenta, Mouse brain and A431 cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab103671 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 43 kDa.

Target

  • Function
    Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway.
  • Sequence similarities
    Belongs to the GTR/RAG GTP-binding protein family.
  • Cellular localization
    Cytoplasm. Lysosome.
  • Information by UniProt
  • Database links
  • Alternative names
    • GTP-binding protein ragB antibody
    • Rag B antibody
    • RagB antibody
    • Ras-related GTP-binding protein B antibody
    • RRAGB antibody
    • RRAGB_HUMAN antibody
    see all

Images

  • Anti-RRAGB antibody (ab103671) at 1/500 dilution + Human placenta tissue lysate at 50 µg

    Predicted band size : 43 kDa
  • Anti-RRAGB antibody (ab103671) at 1/500 dilution + Mouse brain tissue lysate at 50 µg

    Predicted band size : 43 kDa
  • Anti-RRAGB antibody (ab103671) at 1/500 dilution + A431 cell lysate at 50 µg

    Predicted band size : 43 kDa
  • All lanes : Anti-RRAGB antibody (ab103671) at 1/500 dilution

    Lane 1 : RRAGB transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 43 kDa

References

ab103671 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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