Overview

  • Product name
    Anti-RRAGC antibody [2938C3a]
    See all RRAGC primary antibodies
  • Description
    Mouse monoclonal [2938C3a] to RRAGC
  • Tested applications
    Suitable for: WB, Dot blotmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment comprising of 50-200 amino acids from near the N terminus of Human RRAGC (NM_022157).

  • Positive control
    • Recombinant fragment of human RRAGC.

Properties

Applications

Our Abpromise guarantee covers the use of ab76577 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 - 2 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 44 kDa).
Dot blot Use at an assay dependent dilution.

Target

  • Function
    Has guanine nucleotide-binding activity but weak intrinsic GTPase activity. Probably required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids.
  • Sequence similarities
    Belongs to the GTR/RAG GTP-binding protein family.
  • Cellular localization
    Cytoplasm. Nucleus. Lysosome. Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA.
  • Information by UniProt
  • Database links
  • Alternative names
    • AU041672 antibody
    • FLJ13311 antibody
    • GTPase interacting protein 2 antibody
    • GTPase-interacting protein 2 antibody
    • GTR2 antibody
    • MGC47404 antibody
    • OTTHUMP00000000548 antibody
    • Rag C antibody
    • Rag C protein antibody
    • RAGC antibody
    • Ras related GTP binding C antibody
    • Ras-related GTP-binding protein C antibody
    • RP23 29H22.4 antibody
    • RRAGC antibody
    • RRAGC_HUMAN antibody
    • TIB929 antibody
    • YGR163W antibody
    see all

Images

References

ab76577 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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