Overview

  • Product nameAnti-RREB1 antibody
    See all RREB1 primary antibodies
  • Description
    Rabbit polyclonal to RREB1
  • Tested applicationsSuitable for: WB, ELISA, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Recombinant full length protein (Mouse)

  • Positive control
    • Murine kidney tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab64168 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 184 kDa.
ELISA 1/2000 - 1/10000.
IHC-P Use a concentration of 10 µg/ml.
ICC/IF Use at an assay dependent concentration.

Target

  • FunctionTranscription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1.
  • Tissue specificityExpressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain.
  • Sequence similaritiesBelongs to the krueppel C2H2-type zinc-finger protein family.
    Contains 15 C2H2-type zinc fingers.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationNucleus speckle.
  • Information by UniProt
  • Database links
  • Alternative names
    • FINB antibody
    • Finger protein in nuclear bodies antibody
    • Hindsight homolog antibody
    • HNT antibody
    • LZ321 antibody
    • Raf responsive zinc finger protein LZ321 antibody
    • Raf-responsive zinc finger protein LZ321 antibody
    • RAS responsive element binding protein 1 antibody
    • Ras-responsive element-binding protein 1 antibody
    • RREB 1 antibody
    • RREB-1 antibody
    • Rreb1 antibody
    • RREB1_HUMAN antibody
    • Zep 1 antibody
    • Zep-1 antibody
    • Zep1 antibody
    • Zinc finger motif enhancer binding protein 1 antibody
    • Zinc finger motif enhancer-binding protein 1 antibody
    see all

Anti-RREB1 antibody images

  • ab64168 at 10µg/ml staining RREB1 in mouse kidney by Immunohistochemistry, Formalin-fixed, paraffin-embedded tissue.

References for Anti-RREB1 antibody (ab64168)

This product has been referenced in:
  • Kent OA  et al. RREB1 repressed miR-143/145 modulates KRAS signaling through downregulation of multiple targets. Oncogene : (2012). Read more (PubMed: 22751122) »
  • Pramanik D  et al. Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. Mol Cancer Ther 10:1470-80 (2011). IHC-P ; Mouse . Read more (PubMed: 21622730) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"