Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA).
Use a concentration of 1 µg/ml. This antibody gave a positive result in ELISA against the immunizing peptide (ab98174).
FunctionTranscription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1.
Tissue specificityExpressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain.
Sequence similaritiesBelongs to the krueppel C2H2-type zinc-finger protein family. Contains 15 C2H2-type zinc fingers.
Post-translational modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.