Overview

  • Product nameAnti-RRM2 antibodySee all RRM2 primary antibodies ...
  • Description
    Chicken polyclonal to RRM2
  • Specificityab26170 recognises Ribonucleoside-diphosphate reductase M2 subunit.
  • Tested applicationsWBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide: MLSLRVPLAP ITDPQQLQLS PLKGLSLVDK ENTPPALSGT RVLASKTARR IFQEPTEPKT KAAAPGVEDE PLLRENPRRF VIFPIEYHDI WQ, corresponding to amino acids 1-92 of Human RRM2

Properties

  • FormLiquid
  • Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein L purified
  • Clonality Polyclonal
  • IsotypeIgY
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab26170 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000. Predicted molecular weight: 45 kDa.

Target

  • FunctionProvides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
  • PathwayGenetic information processing; DNA replication.
  • Sequence similaritiesBelongs to the ribonucleoside diphosphate reductase small chain family.
  • Post-translational
    modifications
    Phosphorylation on Ser-20 relieves the inhibitory effect on Wnt signaling.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • R2 antibody
    • Ribonucleoside diphosphate reductase M2 subunit antibody
    • Ribonucleoside-diphosphate reductase subunit M2 antibody
    • Ribonucleotide reductase M2 antibody
    • Ribonucleotide reductase M2 polypeptide antibody
    • Ribonucleotide reductase M2 subunit antibody
    • Ribonucleotide reductase small chain antibody
    • Ribonucleotide reductase small subunit antibody
    • RIR2_HUMAN antibody
    • RR 2 antibody
    • RR2 antibody
    • RR2M antibody
    • RRM 2 antibody
    • RRM2 antibody
    see all

Anti-RRM2 antibody images

  • Anti-RRM2 antibody (ab26170) at 1/2000 dilution + E coli-derived RRM2 fusion protein

    Secondary
    Goat anti-IgY-HRP diluted 1/1000

    Predicted band size : 45 kDa

References for Anti-RRM2 antibody (ab26170)

ab26170 has not yet been referenced specifically in any publications.

Product Wall

Abreviews
Application Western blot
Sample Human Cell lysate - whole cell (fibroblast)
Loading amount 10000 cells
Specification fibroblast
Gel Running Conditions Reduced Denaturing (4-20% acrylamide SDS-PAGE)
Blocking step Milk as blocking agent for 8 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 4°C
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Submitted Feb 24 2009

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"