Overview

  • Product nameAnti-RRP4 antibody
    See all RRP4 primary antibodies
  • Description
    Rabbit polyclonal to RRP4
  • Tested applicationsSuitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant fragment, corresponding to amino acids 1-237 of Human RRP4 (AAH00747).

  • Positive control
    • HeLa, A549, HepG2 and HCT116 cells and whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab111810 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 33 kDa.
ICC/IF 1/100 - 1/500.

Target

  • RelevanceThe exosome, present in both the nucleus and cytoplasm of all eukaryotic cells, is a complex of 3'-5' exoribonucleases containing at least nine core components. Recently, it has been demonstrated, mainly by analyses in yeast, that the nuclear exosome is essential for rRNA processing and sn(o)RNA biogenesis. Furthermore, it is involved in the degradation of improperly processed mRNAs. The cytoplasmic exosome participates in normal mRNA turnover and in the degradation of inherently instable mRNAs that contain AU-rich elements. Therefore, the exosome plays a key role in RNA metabolism.
  • Cellular localizationCytoplasmic, Exosome and Nuclear
  • Database links
  • Alternative names
    • EXOSC2 antibody
    • Exosome complex exonuclease RRP4 antibody
    • Exosome component 2 antibody
    • Homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4) antibody
    • Homolog of yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease antibody
    • hRrp4p antibody
    • OTTHUMP00000022370 antibody
    • OTTHUMP00000022371 antibody
    • OTTHUMP00000022372 antibody
    • OTTHUMP00000022373 antibody
    • OTTHUMP00000022374 antibody
    • p7 antibody
    • Ribosomal RNA processing protein 4 antibody
    • RRP4 antibody
    • Rrp4p antibody
    see all

Anti-RRP4 antibody images

  • Anti-RRP4 antibody (ab111810) at 1/1000 dilution + HCT116 whole cell lysate at 30 µg

    Predicted band size : 33 kDa
  • ab1810 at 1/200 dilution staining RRP4 in paraformaldehyde-fixed HeLa cells by Immunofluorescence. The lower image is costained with Hoechst 33342.

References for Anti-RRP4 antibody (ab111810)

ab111810 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"