• Product nameAnti-RRP4 antibody
    See all RRP4 primary antibodies
  • Description
    Rabbit polyclonal to RRP4
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Guinea pig, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide: AMEMRLPVAR KPLSERLGRD TKKHLVVPGD TITTDTGFMR GHGTYMGEEK, corresponding to amino acids 2-51 of Human RRP4

  • Positive control
    • Jurkat cell lysate.


Associated products


Our Abpromise guarantee covers the use of ab66666 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1/1562500.

IHC-P Use a concentration of 4 - 8 µg/ml.


  • RelevanceThe exosome, present in both the nucleus and cytoplasm of all eukaryotic cells, is a complex of 3'-5' exoribonucleases containing at least nine core components. Recently, it has been demonstrated, mainly by analyses in yeast, that the nuclear exosome is essential for rRNA processing and sn(o)RNA biogenesis. Furthermore, it is involved in the degradation of improperly processed mRNAs. The cytoplasmic exosome participates in normal mRNA turnover and in the degradation of inherently instable mRNAs that contain AU-rich elements. Therefore, the exosome plays a key role in RNA metabolism.
  • Cellular localizationCytoplasmic, Exosome and Nuclear
  • Database links
  • Alternative names
    • EXOSC2 antibody
    • Exosome complex exonuclease RRP4 antibody
    • Exosome component 2 antibody
    • Homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4) antibody
    • Homolog of yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease antibody
    • hRrp4p antibody
    • OTTHUMP00000022370 antibody
    • OTTHUMP00000022371 antibody
    • OTTHUMP00000022372 antibody
    • OTTHUMP00000022373 antibody
    • OTTHUMP00000022374 antibody
    • p7 antibody
    • Ribosomal RNA processing protein 4 antibody
    • RRP4 antibody
    • Rrp4p antibody
    see all

Anti-RRP4 antibody images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human lung tissue labelling RRP4 with ab66666 at 4.0-8.0µg/ml. Positive staining shown in alveolar cells. Magnification: 400X.
  • All lanes : Anti-RRP4 antibody (ab66666) at 1.25 µg/ml

    Lane 1 : Marker
    Lane 2 : Jurkat cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 33 kDa
    Observed band size : 33 kDa
    Additional bands at : 75 kDa. We are unsure as to the identity of these extra bands.
    Gel concentration: 12%

References for Anti-RRP4 antibody (ab66666)

ab66666 has not yet been referenced specifically in any publications.

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