Overview

  • Product name(R,S)-CHPG sodium salt
  • Description
    mGlu5 agonist; water soluble
  • Biological descriptionWater soluble form of (R,S)-CHPG (ab120039), a selective mGlu5 agonist.

    Also available in simple stock solutions (ab144497) - add 1 ml of water to get an exact, ready-to-use concentration.
  • Purity> 99%

Properties

    Associated products

    References for (R,S)-CHPG sodium salt (ab120221)

    This product has been referenced in:
    • Domenici MR  et al. Chronic treatment with the mGlu5R antagonist MPEP reduces the functional effects of the mGlu5R agonist CHPG in the striatum of 6-hydroxydopamine-lesioned rats: possible relevance to the effects of mGlu5R blockade in Parkinson's disease. J Neurosci Res 80:646-54 (2005). Read more (PubMed: 15880742) »
    • Salt TE  et al. Antagonism of the mGlu5 agonist 2-chloro-5-hydroxyphenylglycine by the novel selective mGlu5 antagonist 6-methyl-2-(phenylethynyl)-pyridine (MPEP) in the thalamus. Br J Pharmacol 127:1057-9 (1999). Read more (PubMed: 10455248) »
    • Doherty AJ  et al. (RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but no mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus. Neuropharmacology 36:265-7 (1997). Read more (PubMed: 9144665) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"