(R,S)-Sulforaphane, antagonist of Ah receptor (ab141969)
Key features and details
- Potent, non-competitive antagonist of Ah receptor
- CAS Number: 4478-93-7
- Purity: > 98%
Soluble in DMSO to 100 mM
- Form / State: Liquid
- Source: Synthetic
Overview
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Product name
(R,S)-Sulforaphane, antagonist of Ah receptor -
Description
Potent, non-competitive antagonist of Ah receptor -
Purity
> 98% -
General notes
This compound is a neat liquid at room temperature, clear to slightly yellow in color. It is not dissolved in solvent. In small quantities the material will coat the sides of the ampule it is shipped in and may appear to be invisible, or it may be trapped in the tip of the ampule. Wash the upper and lower parts of the ampule with solvent to ensure all of the material is obtained.
Protect from air and light. Prolonged exposure to direct sunlight leads to release of iodine from the sodium diatrizoate molecule.
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CAS Number
4478-93-7 -
Chemical structure
Properties
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Chemical name
1-Isothiocyanato-4-methylsulfinylbutane
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Molecular weight
177.29 -
Molecular formula
C6H11NOS2 -
PubChem identifier
5350 -
Storage instructions
Shipped at Room Temperature. Store at -20°C. Store In the Dark. -
Solubility overview
Soluble in DMSO to 100 mM
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CS(=O)CCCCN=C=S -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab141969 has been referenced in 3 publications.
- Kyriakou S et al. Polyphenolics, glucosinolates and isothiocyanates profiling of aerial parts of Nasturtium officinale (Watercress). Front Plant Sci 13:998755 (2022). PubMed: 36457522
- Li S et al. Protective effects of sulforaphane on diabetic retinopathy: activation of the Nrf2 pathway and inhibition of NLRP3 inflammasome formation. Exp Anim 68:221-231 (2019). PubMed: 30606939
- Bi M et al. Sulphoraphane Improves Neuronal Mitochondrial Function in Brain Tissue in Acute Carbon Monoxide Poisoning Rats. Basic Clin Pharmacol Toxicol 120:541-549 (2017). PubMed: 27983767