Biological descriptionD2-like dopamine receptor antagonist. Shows antipsychotic activity. Active enantiomer (S)-sulpiride (ab120579) also available.
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM and in 1 eq. HCl to 50 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Seeman P & Van Tol HH Dopamine D4 receptors bind inactive (+)-aporphines, suggesting neuroleptic role. Sulpiride not stereoselective. Eur J Pharmacol233:173-4 (1993).
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Van der Niepen P et al. Hypotensive and regional hemodynamic effects of the dopamine receptor agonist SK & F 85174 in the anesthetized rat. Arch Int Pharmacodyn Ther313:98-107 (0).
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