Overview

  • Product nameAnti-RSK3 antibody
    See all RSK3 primary antibodies
  • Description
    Rabbit polyclonal to RSK3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Rat
    Predicted to work with: Mouse, Chicken, Cow, Dog, Human
  • Immunogen

    Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat ribosomal RSK3, comjugated to KLH. The amino acid sequence is not available.

  • Positive control
    • Rat hippocampal lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab42934 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 90 kDa.

Target

  • FunctionSerine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells.
  • Tissue specificityWidely expressed with higher expression in lung, skeletal muscle, brain, uterus, ovary, thyroid and prostate.
  • Sequence similaritiesBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 2 protein kinase domains.
  • Post-translational
    modifications
    Activated by phosphorylation at Ser-218 by PDPK1. Autophosphorylated on Ser-377, as part of the activation process. May be phosphorylated at Thr-356 and Ser-360 by MAPK1/ERK2 and MAPK3/ERK1.
    N-terminal myristoylation results in an activated kinase in the absence of added growth factors.
  • Cellular localizationNucleus. Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • 90 kDa ribosomal protein S6 kinase 2 antibody
    • HU 2 antibody
    • KS6A2_HUMAN antibody
    • MAP kinase activated protein kinase 1c antibody
    • MAP kinase-activated protein kinase 1c antibody
    • MAPK-activated protein kinase 1c antibody
    • MAPKAP kinase 1c antibody
    • MAPKAPK-1c antibody
    • MAPKAPK1C antibody
    • Mitogen.activated protein kinase-activated protein kinase 1C antibody
    • p90 RSK3 antibody
    • p90-RSK 2 antibody
    • p90RSK2 antibody
    • pp90RSK3 antibody
    • Ribosomal protein S6 kinase alpha-2 antibody
    • ribosomal protein S6 kinase, 90kDa, polypeptide 2 antibody
    • Ribosomal S6 kinase 3 antibody
    • RPS6KA2 antibody
    • RSK 3 antibody
    • RSK antibody
    • RSK-3 antibody
    • S6K alpha antibody
    • S6K alpha 2 antibody
    • S6K-alpha-2 antibody
    see all

Anti-RSK3 antibody images

References for Anti-RSK3 antibody (ab42934)

ab42934 has not yet been referenced specifically in any publications.

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