Anti-RTEL1 antibody (ab85557)
Key features and details
- Rabbit polyclonal to RTEL1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-RTEL1 antibody -
Description
Rabbit polyclonal to RTEL1 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Synthetic peptide corresponding to N-terminal residues of human RTEL1
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Positive control
- Small intestine tissue
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.01% Sodium azide
Constituents: PBS, 50% Glycerol -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab85557 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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Notes |
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IHC-P
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Relevance
RTEL1 (Regulator of telomere elongation helicase 1) is probably an ATP-dependent DNA helicase. RTEL1 is a member of the stathmin family, and is related to RAD3/ERCC2, a plasma membrane Ras-related GTPase. The amplification or overexpression of this gene may contribute to cell growth and tumor progression. It is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes, such as TNFRSF6B. -
Cellular localization
Nuclear -
Database links
- Entrez Gene: 51750 Human
- Entrez Gene: 269400 Mouse
- Omim: 608833 Human
- SwissProt: Q9NZ71 Human
- SwissProt: Q0VGM9 Mouse
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Alternative names
- bK3184A7.3 antibody
- C20orf41 antibody
- Chromosome 20 open reading frame 41 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab85557 has not yet been referenced specifically in any publications.