The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 152 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
Use at an assay dependent dilution.
RelevanceRTEL1 (Regulator of telomere elongation helicase 1) is probably an ATP-dependent DNA helicase. RTEL1 is a member of the stathmin family, and is related to RAD3/ERCC2, a plasma membrane Ras-related GTPase. The amplification or overexpression of this gene may contribute to cell growth and tumor progression. It is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes, such as TNFRSF6B.